Description

[(Triethylsilyl)Oxy]Methyl]-Pyrrolidine is a specialized organosilicon-protected pyrrolidine derivative, a key building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile chiral intermediate and protecting group reagent, enabling complex multi-step syntheses with high selectivity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug molecules, including potential candidates for central nervous system (CNS) and antiviral therapies.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Amino Acid & Peptide Chemistry: Serves as a protected form of a proline-like structure or as a reagent for introducing silyl-protected amino functionalities.
• Agrochemical Synthesis: Employed in the research and production of advanced, stereochemically defined pesticides and herbicides.
• Material Science Research: Investigated as a monomer or functionalization agent for creating novel polymers and silicon-containing hybrid materials.
• Academic & Process R&D: A valuable tool for methodological development in organic synthesis within university and industrial R&D laboratories.

Basic Information

Product Name	[(Triethylsilyl)Oxy]Methyl]-Pyrrolidine
CAS No.	1061307-56-9
Molecular Formula	C12H27NOSi
Molecular Weight	229.44 g/mol
Synonyms	1-[[(Triethylsilyl)oxy]methyl]pyrrolidine; N-[[(Triethylsilyl)oxy]methyl]pyrrolidine; (Triethylsilyloxymethyl)pyrrolidine; Pyrrolidine, 1-[[(triethylsilyl)oxy]methyl]-; TES-protected pyrrolidinemethanol; (Pyrrolidin-1-yl)methanol triethylsilyl ether; 1-(Triethylsilyloxymethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our [(Triethylsilyl)Oxy]Methyl]-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high-purity standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.