Description

7-Chloro-3,4-Dihydro-1H-[2,6]Naphthyridine-2-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its naphthyridine core structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in outsourced drug discovery and development services.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and drug design.

Basic Information

Product Name	7-Chloro-3,4-Dihydro-1H-[2,6]Naphthyridine-2-Carboxylic Acid tert-Butyl Ester
CAS No.	1060816-50-3
Molecular Formula	C13H15ClN2O2
Molecular Weight	266.72 g/mol
Synonyms	tert-Butyl 7-chloro-3,4-dihydro-1H-[2,6]naphthyridine-2-carboxylate; 7-Chloro-1,2,3,4-tetrahydro-[2,6]naphthyridine-2-carboxylic acid tert-butyl ester; 7-Chloro-3,4-dihydro-2H-[2,6]naphthyridine-2-carboxylic acid 1,1-dimethylethyl ester; 1060816-50-3; 7-Chloro-1,2,3,4-tetrahydro-2,6-naphthyridine-2-carboxylic acid tert-butyl ester; 7-Chloro-3,4-dihydro-1H-2,6-naphthyridine-2-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 7-Chloro-3,4-Dihydro-1H-[2,6]Naphthyridine-2-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.