Description

Pyridine, 4-Ethynyl-2-Methoxy- is a specialized pyridine derivative featuring both an ethynyl and a methoxy substituent, making it a valuable building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Ligand & Catalyst Development: Serves as a starting material for creating sophisticated ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and advanced organic frameworks due to its conjugated ethynyl group.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes, enabled by its "click chemistry" compatible alkyne functionality.
• Academic & Industrial R&D: A versatile scaffold for exploratory chemistry in university laboratories and corporate R&D centers for novel compound libraries.

Basic Information

Product Name	Pyridine, 4-Ethynyl-2-Methoxy-
CAS No.	1060816-39-8
Molecular Formula	C8H7NO
Molecular Weight	133.15 g/mol
Synonyms	4-Ethynyl-2-methoxypyridine; 2-Methoxy-4-ethynylpyridine; 4-Ethynyl-2-pyridinol methyl ether; 2-Methoxypyridine-4-acetylene; 4-Ethynyl-2-methoxy-pyridine; 2-Methoxy-4-(ethynyl)pyridine; 4-Acetylenyl-2-methoxypyridine
EINECS	Contact for details

Quality Control

Our Pyridine, 4-Ethynyl-2-Methoxy- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.