Description

2-Bromo-5-Chloro-Pyridin-4-Ylamine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic amine scaffold that enables the construction of complex molecules with precision. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and proteomics research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-5-Chloro-Pyridin-4-Ylamine
CAS No.	1060815-72-6
Molecular Formula	C5H4BrClN2
Molecular Weight	207.46 g/mol
Synonyms	4-Amino-2-bromo-5-chloropyridine; 5-Chloro-2-bromopyridin-4-amine; 2-Bromo-5-chloro-4-pyridinamine; 4-Pyridinamine, 2-bromo-5-chloro-; 2-Bromo-5-chloro-4-aminopyridine; 5-Chloro-2-bromo-4-aminopyridine; 2-Bromo-5-chloro-4-pyridylamine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloro-Pyridin-4-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.