Description

1-(5-Trifluoromethoxy-Pyridin-2-Yl)-Ethanone is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a trifluoromethoxy substituent, imparts unique electronic and steric properties essential for developing novel compounds with enhanced biological activity and material characteristics. This intermediate is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the creation of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethoxy group can improve metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for synthesizing specialized ligands, catalysts, and fluorinated organic materials with tailored electronic properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring novel fluorination chemistry and constructing complex heterocyclic frameworks.

Basic Information

Product Name	1-(5-Trifluoromethoxy-Pyridin-2-Yl)-Ethanone
CAS No.	1060814-98-3
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2-Acetyl-5-(trifluoromethoxy)pyridine; 1-[5-(Trifluoromethoxy)pyridin-2-yl]ethanone; 5-(Trifluoromethoxy)-2-acetylpyridine; Ethanone, 1-[5-(trifluoromethoxy)-2-pyridinyl]-; 2-Pyridinyl, 5-(trifluoromethoxy)-, ethanone deriv.
EINECS	Contact for details

Quality Control

Our 1-(5-Trifluoromethoxy-Pyridin-2-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.