Description

tert-Butyl ((4-Bromopyridin-2-Yl)Methyl)Carbamate is a high-purity, protected amine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing functionalized pyridine scaffolds.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and develop new drug candidates.
• Peptidomimetic Synthesis: Serves as a protected amino-methyl pyridine building block for creating peptide analogs and mimetics.
• Agrochemical Development: Employed in the research and production of advanced crop protection agents and herbicides.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for metal catalysis or functional materials.
• Custom Chemical Synthesis: Provides a versatile handle for contract research organizations (CROs) and CDMOs to perform bespoke synthesis for clients.

Basic Information

Product Name	tert-Butyl ((4-Bromopyridin-2-Yl)Methyl)Carbamate
CAS No.	1060813-12-8
Molecular Formula	C11H15BrN2O2
Molecular Weight	287.15 g/mol
Synonyms	Boc-4-Bromo-2-pyridylmethylamine; N-Boc-2-(Aminomethyl)-4-bromopyridine; 1,1-Dimethylethyl N-[(4-bromo-2-pyridinyl)methyl]carbamate; tert-Butyl N-[(4-bromopyridin-2-yl)methyl]carbamate; 2-((tert-Butoxycarbonyl)aminomethyl)-4-bromopyridine; 4-Bromo-2-((Boc-amino)methyl)pyridine; (4-Bromo-pyridin-2-ylmethyl)-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl ((4-Bromopyridin-2-Yl)Methyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.