Description

tert-Butyl n-[(3-Bromopyridin-4-Yl)Methyl]Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a brominated pyridine core protected by a Boc (tert-butoxycarbonyl) group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of complex bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel drug candidates, particularly in kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery projects.
• Kinase Inhibitor Development: Serves as a crucial precursor in the construction of heterocyclic scaffolds common in kinase inhibitor libraries.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis and scale-up projects.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.

Basic Information

Product Name	tert-Butyl n-[(3-Bromopyridin-4-Yl)Methyl]Carbamate
CAS No.	1060813-11-7
Molecular Formula	C11H15BrN2O2
Molecular Weight	287.16 g/mol
Synonyms	Boc-4-(aminomethyl)-3-bromopyridine; tert-Butyl (3-bromopyridin-4-yl)methylcarbamate; 3-Bromo-4-((((tert-butoxy)carbonyl)amino)methyl)pyridine; 4-((tert-Butoxycarbonylamino)methyl)-3-bromopyridine; 1-Boc-3-bromo-4-(aminomethyl)pyridine; (3-Bromo-4-pyridylmethyl)carbamic acid tert-butyl ester; N-Boc-3-bromo-4-(aminomethyl)pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[(3-Bromopyridin-4-Yl)Methyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.