Description

2-Pyridinecarbonitrile, 5-(2-Aminoethyl)- is a specialized pyridine derivative featuring both a nitrile and a primary aminoethyl functional group, making it a versatile and valuable bifunctional building block. This compound is critical for the synthesis of complex heterocyclic molecules and active pharmaceutical ingredients (APIs) due to its reactive handles for further chemical elaboration. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Fine Chemical Manufacturing: Acts as a building block for the custom synthesis of complex, high-value specialty chemicals.
• Academic and Industrial R&D: Fundamental research reagent for exploring new organic reactions and synthetic methodologies.

Basic Information

Product Name	2-Pyridinecarbonitrile, 5-(2-Aminoethyl)-
CAS No.	1060812-29-4
Molecular Formula	C8H9N3
Molecular Weight	147.18 g/mol
Synonyms	5-(2-Aminoethyl)picolinonitrile; 5-(2-Aminoethyl)-2-cyanopyridine; 2-Cyano-5-(2-aminoethyl)pyridine; 5-(2-Aminoethyl)pyridine-2-carbonitrile; 2-Pyridinecarbonitrile, 5-(2-aminoethyl)-; (5-(2-Aminoethyl)pyridin-2-yl)methanenitrile
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarbonitrile, 5-(2-Aminoethyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.