Description

1-(2-Chloropyridin-3-Yl)Cyclopropanecarboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring a chloropyridine moiety fused with a strained cyclopropane ring, makes it a critical intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the chloropyridine unit is a common pharmacophore.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials or liquid crystals.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, functionalized cyclopropane derivatives.

Basic Information

Product Name	1-(2-Chloropyridin-3-Yl)Cyclopropanecarboxylic Acid
CAS No.	1060811-81-5
Molecular Formula	C9H8ClNO2
Molecular Weight	197.62 g/mol
Synonyms	1-(2-Chloro-3-pyridinyl)cyclopropanecarboxylic acid; Cyclopropanecarboxylic acid, 1-(2-chloro-3-pyridinyl)-; 1-(2-Chloropyridin-3-yl)cyclopropane-1-carboxylic acid; 3-(1-Carboxycyclopropyl)-2-chloropyridine; 2-Chloro-3-(1-carboxycyclopropyl)pyridine; 1060811-81-5; 1-(2-Chloro-pyridin-3-yl)-cyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Chloropyridin-3-Yl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.