Description

C-[1-(6-Bromo-Pyridin-2-Yl)-Cyclopropyl]-Methylamine is a high-value, synthetically versatile brominated pyridine derivative featuring a cyclopropylmethylamine moiety. This compound serves as a critical pharmaceutical intermediate and organic building block for constructing complex molecules in medicinal chemistry and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Building block for developing novel herbicides, insecticides, and fungicides, leveraging the bioactivity of the pyridine and cyclopropane rings.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its nitrogen-containing heterocyclic structure.
• Material Science: Intermediate for creating advanced organic electronic materials and functional polymers.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and tool compounds for biological target identification and validation.

Basic Information

Product Name	C-[1-(6-Bromo-Pyridin-2-Yl)-Cyclopropyl]-Methylamine
CAS No.	1060811-48-4
Molecular Formula	C9H11BrN2
Molecular Weight	227.10 g/mol
Synonyms	1-(6-Bromopyridin-2-yl)cyclopropanemethanamine; (1-(6-Bromopyridin-2-yl)cyclopropyl)methanamine; 2-Bromo-6-(1-(aminomethyl)cyclopropyl)pyridine; 6-Bromo-2-(1-(aminomethyl)cyclopropyl)pyridine; C-[1-(6-Bromo-2-pyridyl)cyclopropyl]methylamine; (1-(6-Bromo-2-pyridinyl)cyclopropyl)methanamine; 2-(1-(Aminomethyl)cyclopropyl)-6-bromopyridine
EINECS	Contact for details

Quality Control

Our C-[1-(6-Bromo-Pyridin-2-Yl)-Cyclopropyl]-Methylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.