Description

1-(2-Bromopyridin-4-Yl)Cyclopropanecarboxylic Acid is a high-value brominated pyridine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a cyclopropane ring and a halogenated heterocycle, makes it an essential building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine moiety.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Advanced Material Development: A building block for organic electronic materials and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-(2-Bromopyridin-4-Yl)Cyclopropanecarboxylic Acid
CAS No.	1060811-43-9
Molecular Formula	C9H8BrNO2
Molecular Weight	242.07 g/mol
Synonyms	1-(2-Bromo-4-pyridinyl)cyclopropanecarboxylic acid; Cyclopropanecarboxylic acid, 1-(2-bromo-4-pyridinyl)-; 1-(2-Bromopyridin-4-yl)cyclopropane-1-carboxylic acid; 1-(2-Bromo-4-pyridyl)cyclopropanecarboxylic acid; 1-(2-Bromopyridin-4-yl)cyclopropanecarboxylate; 1060811-43-9; 1-(2-Bromopyridin-4-yl)cyclopropanecarboxylic acid (CAS 1060811-43-9)
EINECS	Contact for details

Quality Control

Our 1-(2-Bromopyridin-4-Yl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications in GMP (Good Manufacturing Practice) environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.