Description

1-(6-Bromopyridin-3-Yl)Cyclopropan-1-Amine is a high-purity, advanced pharmaceutical intermediate featuring a brominated pyridine core fused with a cyclopropylamine moiety. This compound is of significant value for medicinal chemistry research and development, serving as a key building block for constructing novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing potential drug candidates and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its versatile chemical handles.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and pesticides.
• Ligand and Catalyst Development: The bromine atom and amine group make it a valuable starting material for creating novel ligands in transition metal catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific scaffold.

Basic Information

Product Name	1-(6-Bromopyridin-3-Yl)Cyclopropan-1-Amine
CAS No.	1060811-36-0
Molecular Formula	C8H9BrN2
Molecular Weight	213.08 g/mol
Synonyms	1-(6-Bromo-3-pyridinyl)cyclopropanamine; 1-(6-Bromopyridin-3-yl)cyclopropan-1-amine; 6-Bromo-3-(1-aminocyclopropyl)pyridine; 3-(1-Aminocyclopropyl)-6-bromopyridine; 1-(6-Bromo-3-pyridyl)cyclopropylamine; 1-Amino-1-(6-bromopyridin-3-yl)cyclopropane; Cyclopropanamine, 1-(6-bromo-3-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 1-(6-Bromopyridin-3-Yl)Cyclopropan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.