Description

6-Bromo-4-Chloropicolinic Acid is a high-purity halogenated picolinic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working in pharmaceutical intermediates, crop protection agents, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used as a precursor in the manufacture of novel herbicides, fungicides, and plant growth regulators, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized chelating ligands and metal-organic complexes used in catalysis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for advanced materials, such as organic semiconductors or metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A vital raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	6-Bromo-4-Chloropicolinic Acid
CAS No.	1060811-25-7
Molecular Formula	C6H3BrClNO2
Molecular Weight	236.45 g/mol
Synonyms	4-Chloro-6-bromopicolinic acid; 6-Bromo-4-chloro-2-pyridinecarboxylic acid; 2-Pyridinecarboxylic acid, 6-bromo-4-chloro-; Picolinic acid, 6-bromo-4-chloro-; 6-Bromo-4-chloropyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Chloropicolinic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.