Description

2-Bromo-6-Chloro-Pyridine-4-Carbaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated aldehyde structure makes it an indispensable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its reactive halogen and aldehyde functionalities.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for biochemical and diagnostic research.

Basic Information

Product Name	2-Bromo-6-Chloro-Pyridine-4-Carbaldehyde
CAS No.	1060811-22-4
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	6-Chloro-2-bromopyridine-4-carboxaldehyde; 4-Pyridinecarboxaldehyde, 2-bromo-6-chloro-; 2-Bromo-6-chloro-4-formylpyridine; 2-Bromo-6-chloropyridine-4-carbaldehyde; 2-Bromo-6-chloroisonicotinaldehyde; 1060811-22-4; 2-Bromo-6-chloro-4-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Chloro-Pyridine-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.