Description

1-[2-(Trifluoromethyl)-3-Pyridinyl]Ethanone is a high-purity fluorinated pyridine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its core value lies in the unique reactivity and stability imparted by the trifluoromethyl group, enabling the construction of complex molecules with enhanced properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in regulated industries.
• Organic Synthesis Reagent: A versatile reagent in cross-coupling reactions, nucleophilic substitutions, and other transformations to introduce the 2-(trifluoromethyl)pyridin-3-yl moiety.

Basic Information

Product Name	1-[2-(Trifluoromethyl)-3-Pyridinyl]Ethanone
CAS No.	1060810-84-5
Molecular Formula	C8H6F3NO
Molecular Weight	189.14 g/mol
Synonyms	2'-Trifluoromethyl-3'-acetylpyridine; 1-(2-(Trifluoromethyl)pyridin-3-yl)ethan-1-one; 3-Acetyl-2-(trifluoromethyl)pyridine; Ethanone, 1-[2-(trifluoromethyl)-3-pyridinyl]-; 2-(Trifluoromethyl)nicotinoyl methyl ketone; 1-(2-Trifluoromethylpyridin-3-yl)ethanone
EINECS	Contact for details

Quality Control

Our production of 1-[2-(Trifluoromethyl)-3-Pyridinyl]Ethanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. All material is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting compliance in GMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider maintaining the material under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.