Description

4-Chloro-6-Trifluoromethyl-Nicotinic Acid is a high-value, multi-functional chemical intermediate characterized by its halogenated pyridine core. This compound matters for its role as a critical building block in the synthesis of advanced agrochemicals and active pharmaceutical ingredients (APIs), where its unique trifluoromethyl and chloro substituents impart desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and production managers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new crop protection agents and novel therapeutic compounds.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of novel APIs, particularly in areas requiring fluorinated motifs for enhanced potency and pharmacokinetics.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science applications.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and other transformations to introduce the chloronicotinate moiety into more complex molecular architectures.

Basic Information

Product Name	4-Chloro-6-Trifluoromethyl-Nicotinic Acid
CAS No.	1060810-66-3
Molecular Formula	C7H3ClF3NO2
Molecular Weight	225.55 g/mol
Synonyms	4-Chloro-6-(trifluoromethyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 4-chloro-6-(trifluoromethyl)-; 4-Chloro-6-trifluoromethylnicotinic acid; 4-Chloro-6-(trifluoromethyl)nicotinic acid; 6-Trifluoromethyl-4-chloronicotinic acid; 4-Chloro-6-trifluoromethyl-3-pyridinecarboxylic acid; 1060810-66-3
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Trifluoromethyl-Nicotinic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.