Description

4-Bromo-6-(Trifluoromethyl)Nicotinaldehyde is a high-value, multi-functional chemical intermediate characterized by its bromine and trifluoromethyl substituents on a nicotinaldehyde core. This compound is critical for facilitating complex molecular transformations in advanced synthetic chemistry, offering a strategic handle for cross-coupling reactions and further functionalization. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to construct biaryl systems.
• Ligand and Catalyst Development: Employed in the design and synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Bromo-6-(Trifluoromethyl)Nicotinaldehyde
CAS No.	1060810-63-0
Molecular Formula	C7H3BrF3NO
Molecular Weight	253.01 g/mol
Synonyms	4-Bromo-6-(trifluoromethyl)pyridine-3-carbaldehyde; 3-Pyridinecarboxaldehyde, 4-bromo-6-(trifluoromethyl)-; 4-Bromo-6-trifluoromethylnicotinaldehyde; 4-Bromo-6-(trifluoromethyl)-3-pyridinecarboxaldehyde; 1060810-63-0; 4-Bromo-6-(trifluoromethyl)nicotinaldehyde
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-(Trifluoromethyl)Nicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.