Description

4-Bromo-6-Methoxy-Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both bromine and methoxy substituents on the pyridine core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig aminations.
• Material Science Research: Employed in the development of organic electronic materials, including charge-transport layers and light-emitting components.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Utilized in research laboratories for exploring new chemical reactions and developing novel heterocyclic compounds.

Basic Information

Product Name	4-Bromo-6-Methoxy-Pyridine-2-Carboxylic Acid
CAS No.	1060810-46-9
Molecular Formula	C7H6BrNO3
Molecular Weight	232.03 g/mol
Synonyms	2-Pyridinecarboxylic acid, 4-bromo-6-methoxy-; 4-Bromo-6-methoxypicolinic acid; 6-Methoxy-4-bromopicolinic acid; 4-Bromo-6-methoxypyridine-2-carboxylic acid; 4-Bromo-6-methoxy-2-pyridinecarboxylic acid; 4-Bromo-6-methoxy-2-picolinic acid; 1060810-46-9 (CAS)
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Methoxy-Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.