Description

5-Chloro-2-(Trifluoromethyl)Pyridin-4-Amine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, makes it an essential intermediate for creating compounds with tailored biological activity and material properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers, liquid crystals, and electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Chloro-2-(Trifluoromethyl)Pyridin-4-Amine
CAS No.	1060810-26-5
Molecular Formula	C6H4ClF3N2
Molecular Weight	196.56 g/mol
Synonyms	4-Amino-5-chloro-2-(trifluoromethyl)pyridine; 5-Chloro-2-trifluoromethyl-4-pyridinamine; 5-Chloro-α,α,α-trifluoro-4-pyridinamine; 2-(Trifluoromethyl)-5-chloropyridin-4-amine; 4-Pyridinamine, 5-chloro-2-(trifluoromethyl)-; 5-Chloro-2-(trifluoromethyl)-4-aminopyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Trifluoromethyl)Pyridin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates for research and regulated development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.