Description

2-Bromo-6-Methylnicotinic Acid is a versatile and high-purity brominated nicotinic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex heterocyclic scaffolds, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings.
• Material Science Research: Employed in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) due to its functionalizable carboxylic acid and halogen groups.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A key raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Bromo-6-Methylnicotinic Acid
CAS No.	1060810-09-4
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	6-Methyl-2-bromonicotinic acid; 2-Bromo-6-methylpyridine-3-carboxylic acid; 3-Carboxy-2-bromo-6-methylpyridine; 2-Bromo-6-picolinic acid, 6-methyl-; Nicotinic acid, 2-bromo-6-methyl-; 1060810-09-4; 2-Bromo-6-methyl-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-Methylnicotinic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.