Description

2-Pyridinecarboxaldehyde, 6-Bromo-4-Fluoro- is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromo and fluoro substituents, makes it an essential precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used in the creation of advanced herbicides, fungicides, and pesticides where the halogenated pyridine core imparts specific biological activity.
• Ligand Synthesis: Serves as a precursor for manufacturing specialized ligands used in catalysis and material science.
• Functional Material Research: Employed in the development of organic electronic materials, such as OLEDs and sensors, due to its modifiable aromatic system.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological mechanisms and target engagement.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form complex biaryl structures.

Basic Information

Product Name	2-Pyridinecarboxaldehyde, 6-Bromo-4-Fluoro-
CAS No.	1060809-22-4
Molecular Formula	C6H3BrFNO
Molecular Weight	204.00 g/mol
Synonyms	6-Bromo-4-fluoropyridine-2-carboxaldehyde; 4-Fluoro-6-bromopicolinaldehyde; 2-Formyl-6-bromo-4-fluoropyridine; 6-Bromo-4-fluoro-2-pyridinecarboxaldehyde; 6-Bromo-4-fluoropicolinaldehyde; 4-Fluoro-6-bromopyridine-2-carbaldehyde; (6-Bromo-4-fluoropyridin-2-yl)methanal; 2-Pyridinecarboxaldehyde, 6-bromo-4-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxaldehyde, 6-Bromo-4-Fluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.