Description

2-Chloro-4-Fluoropyridine-3-Carbaldehyde is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique halogenated pyridine core structure makes it a critical intermediate for constructing complex molecules with tailored biological and physical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-4-Fluoropyridine-3-Carbaldehyde
CAS No.	1060809-21-3
Molecular Formula	C6H3ClFNO
Molecular Weight	159.54 g/mol
Synonyms	3-Formyl-2-chloro-4-fluoropyridine; 2-Chloro-4-fluoro-3-pyridinecarboxaldehyde; 2-Chloro-4-fluoronicotinaldehyde; 4-Fluoro-2-chloropyridine-3-carbaldehyde; 1060809-21-3; 2-Chloro-4-fluoro-3-formylpyridine; 3-Pyridinecarboxaldehyde, 2-chloro-4-fluoro-
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Fluoropyridine-3-Carbaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and GC-MS, is supplied with each shipment to guarantee traceability, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its sensitivity, the container should be kept under an inert atmosphere (e.g., nitrogen) after opening to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.