Description

1-(4-Chloropyridin-2-Yl)-2,2,2-Trifluoroethanamine is a high-value, multi-functional chemical intermediate featuring a chloropyridine core and a trifluoroethylamine side chain. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceuticals and agrochemicals, where its unique halogenated and fluorinated structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the chloropyridine moiety for enhanced efficacy.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or organic semiconductors, where fluorine substitution tunes electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up services.

Basic Information

Product Name	1-(4-Chloropyridin-2-Yl)-2,2,2-Trifluoroethanamine
CAS No.	1060809-07-5
Molecular Formula	C7H6ClF3N2
Molecular Weight	210.58 g/mol
Synonyms	2,2,2-Trifluoro-1-(4-chloro-2-pyridinyl)ethanamine; 1-(4-Chloro-2-pyridinyl)-2,2,2-trifluoroethanamine; 4-Chloro-2-(2,2,2-trifluoroethylamino)pyridine; 2-(4-Chloropyridin-2-yl)-2,2-trifluoroethanamine; 1060809-07-5; 1-(4-Chloropyridin-2-yl)-2,2,2-trifluoroethan-1-amine
EINECS	Contact for details

Quality Control

Our 1-(4-Chloropyridin-2-Yl)-2,2,2-Trifluoroethanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your most critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkali and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.