Description

4-Bromopyridine-2-Sulfonyl Chloride is a versatile and highly reactive chemical building block used in advanced organic synthesis. Its value lies in its dual functionality, serving as a key precursor for the introduction of both bromo and sulfonyl chloride groups into target molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex heterocyclic scaffolds and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structure-activity relationship (SAR) studies.
• Material Science Research: Employed in the creation of functionalized polymers, ligands for catalysis, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation, labeling biomolecules, or creating activity-based probes (ABPs) due to its sulfonyl chloride moiety.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects and the production of specialized fine chemicals on a commercial scale.

Basic Information

Product Name	4-Bromopyridine-2-Sulfonyl Chloride
CAS No.	1060808-87-8
Molecular Formula	C5H3BrClNO2S
Molecular Weight	256.51 g/mol
Synonyms	2-Pyridinesulfonyl chloride, 4-bromo-; 4-Bromo-2-pyridinesulfonyl chloride; 4-Bromopyridine-2-sulfonyl chloride; 4-Bromopyridine-2-sulphonyl chloride; 4-Bromo-pyridine-2-sulfonyl chloride; 1060808-87-8; 4-Bromo-2-sulfonylchloridopyridine
EINECS	Contact for details

Quality Control

Our 4-Bromopyridine-2-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.