Description

4-Fluoro-2-Methoxynicotinic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its molecular structure, featuring both fluorine and methoxy substituents, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized organic materials and liquid crystals for electronic and optical applications.
• Chemical Biology Probes: Utilized to create fluorinated analogs of natural products and biochemical probes for metabolic pathway studies.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Detail
Product Name	4-Fluoro-2-Methoxynicotinic Acid
CAS No.	1060806-71-4
Molecular Formula	C7H6FNO3
Molecular Weight	171.13 g/mol
Synonyms	2-Methoxy-4-fluoronicotinic Acid; 4-Fluoro-2-methoxypyridine-3-carboxylic Acid; 3-Pyridinecarboxylic acid, 4-fluoro-2-methoxy-; 1060806-71-4; 4-Fluoro-2-methoxy-nicotinic acid; 4-Fluoro-2-methoxynicotinic acid; 4-Fluoro-2-methoxy-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-2-Methoxynicotinic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity data, to ensure traceability and compliance with your project specifications. Our quality commitment supports applications requiring high-purity intermediates for GLP (Good Laboratory Practice) and cGMP (current Good Manufacturing Practice) environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The product is stable under recommended conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.