Description

2,2,2-Trifluoro-1-(6-Methylpyridin-3-Yl)Ethanone is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the trifluoroacetyl group, which introduces unique electronic and steric properties essential for modifying molecular activity and stability. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance bioavailability and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials for their unique dielectric properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2,2,2-Trifluoro-1-(6-Methylpyridin-3-Yl)Ethanone
CAS No.	1060806-27-0
Molecular Formula	C8H6F3NO
Molecular Weight	189.13 g/mol
Synonyms	1-(6-Methyl-3-pyridinyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(6-methyl-3-pyridinyl)ethanone; 6-Methyl-3-trifluoroacetylpyridine; 3-Trifluoroacetyl-6-methylpyridine; 2,2,2-Trifluoro-1-(6-methylpyridin-3-yl)ethan-1-one; TFMP Ketone; Trifluoroacetyl-6-methylpyridine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(6-Methylpyridin-3-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.