Description

4-Bromo-6-Chloronicotinaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated aldehyde structure makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its reactive aldehyde and halogen sites for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized heterocyclic compounds for organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for synthesizing labeled compounds and molecular probes for biochemical and diagnostic research applications.

Basic Information

Product Name	4-Bromo-6-Chloronicotinaldehyde
CAS No.	1060805-64-2
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	6-Chloro-4-bromonicotinaldehyde; 4-Bromo-6-chloropyridine-3-carboxaldehyde; 3-Pyridinecarboxaldehyde, 4-bromo-6-chloro-; 4-Bromo-6-chloro-3-formylpyridine; 4-Bromo-6-chloronicotinaldehyde; 1060805-64-2; 4-Bromo-6-chloro-pyridine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Chloronicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support cGMP standards for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.