Description

1-(4-(Trifluoromethyl)Pyridin-2-Yl)Cyclopropanecarboxylic Acid is a high-value, multifunctional organic building block featuring a cyclopropane ring and a trifluoromethylpyridine moiety. This compound is essential for medicinal chemistry research and development, serving as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical, agrochemical, and advanced material research organizations for constructing complex molecules with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of small molecule drugs, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	1-(4-(Trifluoromethyl)Pyridin-2-Yl)Cyclopropanecarboxylic Acid
CAS No.	1060805-58-4
Molecular Formula	C10H8F3NO2
Molecular Weight	231.17 g/mol
Synonyms	2-Cyclopropanecarbonyl-4-(trifluoromethyl)pyridine; 1-[4-(Trifluoromethyl)-2-pyridinyl]cyclopropanecarboxylic Acid; 1-(4-Trifluoromethyl-pyridin-2-yl)-cyclopropanecarboxylic Acid; 1-(4-(Trifluoromethyl)pyridin-2-yl)cyclopropane-1-carboxylic Acid; Cyclopropanecarboxylic acid, 1-[4-(trifluoromethyl)-2-pyridinyl]-; 1060805-58-4
EINECS	Contact for details

Quality Control

Our 1-(4-(Trifluoromethyl)Pyridin-2-Yl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry guidelines for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.