Description

2,2,2-Trifluoro-1-(4-Methylpyridin-2-Yl)Ethanone is a high-value trifluoromethyl ketone derivative, a key building block in modern synthetic chemistry. Its core value lies in its ability to introduce the metabolically stable and lipophilic trifluoromethyl group into complex molecules, significantly altering their physicochemical properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances biological activity and environmental stability.
• Ligand & Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of novel fluorinated polymers, liquid crystals, and organic electronic materials with unique properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring fluorinated ketone chemistry.

Basic Information

Product Name	2,2,2-Trifluoro-1-(4-Methylpyridin-2-Yl)Ethanone
CAS No.	1060804-97-8
Molecular Formula	C8H6F3NO
Molecular Weight	189.14 g/mol
Synonyms	2,2,2-Trifluoro-1-(4-methyl-2-pyridinyl)ethanone; 1-(4-Methylpyridin-2-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(4-methyl-2-pyridyl)ethanone; 4-Methyl-2-(trifluoroacetyl)pyridine; 2-(Trifluoroacetyl)-4-methylpyridine; TFMP Ketone; 4-Methyl-2-pyridyl trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(4-Methylpyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.