Description

[1-(4-Methylpyridin-2-Yl)Cyclopropyl]Methanamine is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclopropylmethylamine-substituted pyridine scaffold. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. Pharmaceutical R&D teams and fine chemical manufacturers need it as a key building block for developing next-generation drugs, including potential kinase inhibitors and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology and neurology research.
• Kinase Inhibitor Development: Serves as a core structural component for designing and screening potential kinase inhibitor libraries.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the cyclopropylmethylamine moiety into complex molecules.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for the cGMP production of clinical trial materials and commercial APIs.
• Agrochemical Intermediate: Potential use in the research and development of advanced crop protection agents with novel modes of action.

Basic Information

Product Name	[1-(4-Methylpyridin-2-Yl)Cyclopropyl]Methanamine
CAS No.	1060804-91-2
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	1-(4-Methyl-2-pyridinyl)cyclopropanemethanamine; 2-(1-(Aminomethyl)cyclopropyl)-4-methylpyridine; (1-(4-Methylpyridin-2-yl)cyclopropyl)methanamine; 4-Methyl-2-(1-(aminomethyl)cyclopropyl)pyridine; CP-AMP; AMP-Cyclopropyl Derivative
EINECS	Contact for details

Quality Control

Our [1-(4-Methylpyridin-2-Yl)Cyclopropyl]Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.