Description

4-Chloro-5-Hydroxy-Pyridine-2-Carboxylic Acid is a versatile pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional reactivity, offering both a carboxylic acid and a halogenated, hydroxylated heterocyclic system. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Chelator Development: Used to create complexing agents for metal catalysis and diagnostic imaging agents.
• Material Science Research: Monomer or functional additive in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Serves as a core structure for designing molecular probes and biochemical tools.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of client-specific, high-value intermediates.

Basic Information

Product Name	4-Chloro-5-Hydroxy-Pyridine-2-Carboxylic Acid
CAS No.	1060804-56-9
Molecular Formula	C6H4ClNO3
Molecular Weight	173.55 g/mol
Synonyms	2-Carboxy-4-chloro-5-hydroxypyridine; 5-Hydroxy-4-chloropicolinic acid; 4-Chloro-5-hydroxypicolinic acid; 4-Chloro-5-hydroxy-2-pyridinecarboxylic acid; 5-Hydroxy-4-chloro-2-pyridinecarboxylic acid; Picolinic acid, 4-chloro-5-hydroxy-; 1060804-56-9
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-5-Hydroxy-Pyridine-2-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.