Description

5-Hydroxy-Pyridine-3-Carbaldehyde is a versatile pyridine derivative and a key heterocyclic building block in advanced organic synthesis. Its unique structure, featuring both an aldehyde and a hydroxyl group on the pyridine ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal catalysis and coordination chemistry, enabling more efficient synthetic transformations.
• Material Science Research: Employed in the creation of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers due to its chelating and reactive sites.
• Chemical Research & Development: Acts as a fundamental scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Used in the multi-step synthesis of complex fine chemicals and specialty additives.

Basic Information

Product Name	5-Hydroxy-Pyridine-3-Carbaldehyde
CAS No.	1060804-48-9
Molecular Formula	C6H5NO2
Molecular Weight	123.11 g/mol
Synonyms	3-Formyl-5-hydroxypyridine; 5-Hydroxynicotinaldehyde; 5-Hydroxypyridine-3-carboxaldehyde; 3-Pyridinecarboxaldehyde, 5-hydroxy-; 5-Hydroxy-3-pyridinecarbaldehyde; 5-Hydroxy-3-formylpyridine; 3-Aldehyde-5-hydroxypyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Hydroxy-Pyridine-3-Carbaldehyde is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and meet your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for prolonged operations to minimize potential oxidation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.