Description

5-Cyano-3-pyridinesulfonyl chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, enabling the efficient introduction of the 5-cyano-3-pyridinesulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients, intermediates for drug discovery, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides that require the pyridine-sulfonyl scaffold.
• Material Science Research: Employed in the development of functional polymers, ligands for catalysis, and advanced organic materials.
• Chemical Biology Probes: Acts as a reagent for modifying proteins or other biomolecules to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A crucial starting material for custom synthesis projects requiring specific sulfonylated heterocycles.

Basic Information

Item	Details
Product Name	5-Cyano-3-pyridinesulfonyl chloride
CAS No.	1060804-15-0
Molecular Formula	C6H3ClN2O2S
Molecular Weight	202.62 g/mol
Synonyms	3-Pyridinesulfonyl chloride, 5-cyano-; 5-Cyanopyridine-3-sulfonyl chloride; 5-Cyano-3-pyridylsulfonyl chloride; 1060804-15-0; 5-Cyanopyridin-3-ylsulfonyl chloride; 3-Pyridinesulfonyl chloride, 5-cyano- (9CI); 5-Cyano-3-pyridinesulfonylchloride
EINECS	Contact for details

Quality Control

Our 5-Cyano-3-pyridinesulfonyl chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.