Description

6-Trifluoromethyl-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functional heterocyclic building block characterized by its fused pyrrolopyridine core and a strategically positioned trifluoromethyl group. This compound is essential for medicinal chemistry and agrochemical research, where it serves as a privileged scaffold for modulating the physicochemical and pharmacokinetic properties of target molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the development of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science: Serves as a precursor for advanced organic electronic materials, including ligands for OLEDs and charge-transport materials.
• Chemical Biology: Employed as a molecular probe or a tagged scaffold for studying protein-ligand interactions and biological pathways.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	6-Trifluoromethyl-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1060802-93-8
Molecular Formula	C8H5F3N2
Molecular Weight	186.14 g/mol
Synonyms	6-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 6-(trifluoromethyl)-; 6-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine; 6-Trifluoromethyl-7-azaindole; 6-CF3-7-azaindole; 6-(Trifluoromethyl)-7-azaindole; TFMPyridine derivative
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethyl-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.