Description

4-Formylnicotinonitrile is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a formyl and a nitrile group, makes it an indispensable intermediate for constructing complex heterocyclic scaffolds. This compound is primarily sought after by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, antiviral agents, and other bioactive nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific pyridine-based architectures.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs) due to its electron-withdrawing and coordinating properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Item	Details
Product Name	4-Formylnicotinonitrile
CAS No.	1060802-57-4
Molecular Formula	C7H4N2O
Molecular Weight	132.12 g/mol
Synonyms	4-Formylnicotinonitrile; 4-Cyano-3-pyridinecarboxaldehyde; 3-Pyridinecarbonitrile, 4-formyl-; 4-Formyl-3-pyridinecarbonitrile; Nicotinonitrile, 4-formyl-; Pyridine-4-carbaldehyde-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Formylnicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.