Description

3-Bromo-4-(Chloromethyl)Pyridine is a versatile and high-value halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional reactivity, featuring both bromine and chloromethyl groups on the pyridine ring, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Building block for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A high-purity intermediate supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-Bromo-4-(Chloromethyl)Pyridine
CAS No.	1060802-26-7
Molecular Formula	C6H5BrClN
Molecular Weight	206.47 g/mol
Synonyms	4-(Chloromethyl)-3-bromopyridine; 3-Bromo-4-chloromethylpyridine; Pyridine, 3-bromo-4-(chloromethyl)-; (3-Bromo-4-pyridinyl)methyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-(Chloromethyl)Pyridine is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are essential for your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.