Description

4-Chloro-5-Methoxypyridine-2-Carbaldehyde is a versatile and high-value heterocyclic building block used in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals due to its reactive aldehyde and halogenated pyridine core. It is primarily sought after by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: Used to synthesize chelating ligands for metal catalysis and organocatalysts.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-Chloro-5-Methoxypyridine-2-Carbaldehyde
CAS No.	1060801-63-9
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	2-Formyl-4-chloro-5-methoxypyridine; 4-Chloro-5-methoxy-2-pyridinecarboxaldehyde; 4-Chloro-5-methoxypicolinaldehyde; 5-Methoxy-4-chloropyridine-2-carbaldehyde; 2-Pyridinecarboxaldehyde, 4-chloro-5-methoxy-; 1060801-63-9
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Methoxypyridine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.