Description

Ethanone, 1-(2-Amino-3-Pyridinyl)-2,2,2-Trifluoro- is a high-purity trifluoromethyl ketone derivative featuring a functionalized aminopyridine core. This compound serves as a critical building block in advanced organic synthesis, enabling the introduction of both fluorine and nitrogen-containing heterocycles into target molecules. It is primarily required by pharmaceutical and agrochemical R&D organizations for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides that leverage the trifluoromethyl group for enhanced bioactivity and environmental stability.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials where fluorine incorporation modifies physical properties.
• Chemical Biology & Proteomics: Serves as a reactive handle or affinity tag in the design of enzyme inhibitors, activity-based probes, and molecular imaging agents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific fluorinated scaffold.

Basic Information

Product Name	Ethanone, 1-(2-Amino-3-Pyridinyl)-2,2,2-Trifluoro-
CAS No.	1060801-31-1
Molecular Formula	C7H5F3N2O
Molecular Weight	190.12 g/mol
Synonyms	1-(2-Amino-3-pyridinyl)-2,2,2-trifluoroethanone; 2-Amino-3-trifluoroacetylpyridine; 2-Amino-3-pyridyl trifluoromethyl ketone; 3-Amino-2-pyridyl trifluoromethyl ketone; 2,2,2-Trifluoro-1-(2-amino-3-pyridinyl)ethanone; 1-(2-Aminopyridin-3-yl)-2,2,2-trifluoroethan-1-one; Trifluoroacetyl-2-amino-3-pyridine; TFAP
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2-Amino-3-Pyridinyl)-2,2,2-Trifluoro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects with material suitable for use under cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.