Description

Ethyl 3-(Trifluoromethyl)-5-pyridinecarboxylate is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a carboxylate ester and a trifluoromethyl group, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the creation of fluorinated probes and tags for studying biological mechanisms and diagnostic applications.
• Advanced Material Synthesis: A building block for novel organic electronic materials and liquid crystals, leveraging its aromatic and fluorinated characteristics.

Basic Information

Product Name	Ethyl 3-(Trifluoromethyl)-5-pyridinecarboxylate
CAS No.	1060794-89-9
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	5-(Ethoxycarbonyl)-3-(trifluoromethyl)pyridine; Ethyl 5-(trifluoromethyl)nicotinate; 3-Trifluoromethyl-pyridine-5-carboxylic acid ethyl ester; 5-Carbethoxy-3-trifluoromethylpyridine; 3-(Trifluoromethyl)pyridine-5-carboxylic acid ethyl ester; Ethyl 3-trifluoromethyl-5-pyridinecarboxylate; 1060794-89-9
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Trifluoromethyl)-5-pyridinecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.