Description

Pyrido[3,4-D]Pyrimidine, 2,4-Dichloro-5,6,7,8-Tetrahydro-7-(Phenylmethyl)- is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical intermediate in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. Researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries need this precise chemical scaffold to accelerate drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry: Core scaffold for constructing libraries of novel bioactive compounds in hit-to-lead and lead optimization stages.
• Agrochemical Research: Building block for developing new active ingredients with herbicidal or fungicidal properties.
• Chemical Biology: Used as a molecular probe or tag to study enzyme function and biological pathways.
• Academic & Contract Research: Essential material for universities and CROs conducting cutting-edge research in heterocyclic chemistry.
• Process Development: Serves as a starting material for scaling up the production of target active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Pyrido[3,4-D]Pyrimidine, 2,4-Dichloro-5,6,7,8-Tetrahydro-7-(Phenylmethyl)-
CAS No.	1059735-34-0
Molecular Formula	C15H15Cl2N3
Molecular Weight	308.20 g/mol
Synonyms	2,4-Dichloro-7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; 7-Benzyl-2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; 2,4-Dichloro-7-(phenylmethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine; 5,6,7,8-Tetrahydro-7-(phenylmethyl)-2,4-dichloropyrido[3,4-d]pyrimidine; Pyrido[3,4-d]pyrimidine, 2,4-dichloro-5,6,7,8-tetrahydro-7-(phenylmethyl)-; 1059735-34-0; 2,4-Dichloro-7-benzyl-5,6,7,8-tetrahydro-pyrido[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our Pyrido[3,4-D]Pyrimidine intermediate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive material from humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.