Description

Ethyl(4As,9Br)-6-Bromo-1,3,4,4A,5,9B-Hexahydro-2H-Pyrido[4,3-B]Indole-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex polycyclic structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Chemical Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Organic Synthesis: A versatile precursor for constructing complex indole- and piperidine-fused heterocyclic scaffolds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying novel synthetic methodologies and reaction mechanisms.

Basic Information

Product Name	Ethyl(4As,9Br)-6-Bromo-1,3,4,4A,5,9B-Hexahydro-2H-Pyrido[4,3-B]Indole-2-Carboxylate
CAS No.	1059630-08-8
Molecular Formula	C14H17BrN2O2
Molecular Weight	325.20 g/mol
Synonyms	Ethyl 6-bromo-1,3,4,4a,5,9b-hexahydro-2H-pyrido[4,3-b]indole-2-carboxylate; 6-Bromo-1,3,4,4a,5,9b-hexahydro-2H-pyrido[4,3-b]indole-2-carboxylic acid ethyl ester; 1059630-08-8; Ethyl 6-bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole-2-carboxylate; UNII-9K5I0W8A0F; SCHEMBL21806227; BCP31033; ZINC000004143756.
EINECS	Contact for details

Quality Control

Every batch of Ethyl(4As,9Br)-6-Bromo-1,3,4,4A,5,9B-Hexahydro-2H-Pyrido[4,3-B]Indole-2-Carboxylate is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet the requirements of cGMP, ICH Q7 guidelines, and relevant pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.