Description

(4As,9Br)-6-Bromo-2,3,4,4A,5,9B-Hexahydro-1H-Pyrido[4,3-B]Indole CAS NO 1059630-07-7 is a high-purity, advanced pharmaceutical intermediate belonging to the complex heterocyclic indole class. This compound is a critical building block in modern organic synthesis, valued for its unique fused ring structure and bromine substitution, which enables precise molecular modifications. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Organic Synthesis Building Block: Provides a versatile scaffold for constructing more complex polycyclic frameworks in academic and industrial R&D.
• Biochemical Probe Development: Acts as a core structure for developing tool compounds and probes used in biological assay development.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	(4As,9Br)-6-Bromo-2,3,4,4A,5,9B-Hexahydro-1H-Pyrido[4,3-B]Indole
CAS No.	1059630-07-7
Molecular Formula	C11H13BrN2
Molecular Weight	253.14 g/mol
Synonyms	6-Bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole; (4aR,9bR)-6-Bromo-1,2,3,4,4a,9b-hexahydro-5H-pyrido[4,3-b]indole; 6-Bromo-1,2,3,4,4a,9b-hexahydro-5H-pyrido[4,3-b]indole; (4aR,9bR)-6-Bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole; 6-Bromo-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole; 1059630-07-7; Pyrido[4,3-b]indole, 6-bromo-2,3,4,4a,5,9b-hexahydro-
EINECS	Contact for details

Quality Control

Our (4As,9Br)-6-Bromo-2,3,4,4A,5,9B-Hexahydro-1H-Pyrido[4,3-B]Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and advanced synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent degradation. This material is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.