Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carbonitrile, 5-(1H-Pyrazol-3-Yl)- is a high-purity, advanced pharmaceutical intermediate featuring a fused heterocyclic core structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery and development, particularly for oncology, antiviral, and kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted small-molecule therapeutics.
• Kinase Inhibitor Development: Serves as a core scaffold for designing potent and selective kinase inhibitors.
• Oncology Research: Used in the discovery of novel anti-cancer agents due to its privileged heterocyclic structure.
• Antiviral Drug Discovery: Employed in medicinal chemistry programs aimed at developing new antiviral compounds.
• Chemical Biology & Proteomics: Utilized as a molecular probe or tag for studying protein-ligand interactions.
• Agrochemical Research: Potential intermediate for developing new active ingredients with specific biological activity.
• Academic & Contract Research: Supplied to universities and CROs for fundamental heterocyclic chemistry and drug discovery projects.
• Custom Synthesis: Available for bespoke chemical synthesis and scale-up services for client-specific molecular targets.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carbonitrile, 5-(1H-Pyrazol-3-Yl)-
CAS No.	1059171-08-2
Molecular Formula	C11H7N5
Molecular Weight	209.21 g/mol
Synonyms	5-(1H-Pyrazol-3-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile; 5-(1H-Pyrazol-3-yl)-7-azaindole-3-carbonitrile; 3-Cyano-5-(1H-pyrazol-3-yl)-1H-pyrrolo[2,3-b]pyridine; 5-(1H-Pyrazol-3-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile; 1059171-08-2; 1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile, 5-(1H-pyrazol-3-yl)-; 5-(1H-Pyrazol-3-yl)-7-azaindole-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Carbonitrile, 5-(1H-Pyrazol-3-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided with every shipment. We can support development projects with material meeting research-grade through to cGMP standards for advanced clinical trials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged manipulation. Keep container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.