Description

2-Bromo-5-Fluoro-Benzenepropanoic Acidethylester is a high-purity fluorinated and brominated aromatic ester building block of significant importance in advanced organic synthesis. This compound is valued for its dual halogen functionality, which provides versatile reactive sites for cross-coupling reactions and further molecular elaboration. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for bioactivity and metabolic stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl structures.
• Functional Group Transformation: The ester group can be hydrolyzed to the corresponding acid or reduced to the alcohol, enabling diverse downstream chemistry.

Basic Information

Product Name	2-Bromo-5-Fluoro-Benzenepropanoic Acidethylester
CAS No.	1057674-00-6
Molecular Formula	C11H12BrFO2
Molecular Weight	275.12 g/mol
Synonyms	Ethyl 3-(2-Bromo-5-fluorophenyl)propanoate; 2-Bromo-5-fluorobenzenepropanoic Acid Ethyl Ester; 3-(2-Bromo-5-fluorophenyl)propionic Acid Ethyl Ester; Benzenepropanoic acid, 2-bromo-5-fluoro-, ethyl ester; Ethyl (2-bromo-5-fluorophenyl)propionate
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Fluoro-Benzenepropanoic Acidethylester is manufactured and tested under strict quality management systems. We ensure high chemical purity and consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee reliable and reproducible performance in your synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.