Description

2-Bromomethyl-5,8-Dioxaspiro[3.4]Octane is a high-value, specialized spirocyclic building block used in advanced organic synthesis. This compound matters for its unique fused ring structure and reactive bromomethyl group, which enables efficient derivatization and incorporation into complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in spirocyclic drug discovery programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the spirocyclic moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing sophisticated chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers and cross-linkers for specialty polymers, resins, and advanced organic frameworks with tailored properties.
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological systems and enzyme mechanisms.
• Academic & Industrial R&D: A versatile starting material for methodological chemistry research and the exploration of new chemical spaces in both university and corporate laboratories.

Basic Information

Item	Detail
Product Name	2-Bromomethyl-5,8-Dioxaspiro[3.4]Octane
CAS No.	1057641-71-0
Molecular Formula	C8H13BrO2
Molecular Weight	221.09 g/mol
Synonyms	5,8-Dioxaspiro[3.4]octane, 2-(bromomethyl)-; 2-(Bromomethyl)-5,8-dioxaspiro[3.4]octane; 2-Bromomethyl-5,8-dioxaspiro[3.4]octane; Spiro[3.4]octane-2-bromomethyl-5,8-dioxide; Bromomethyl Dioxaspirooctane; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-Bromomethyl-5,8-Dioxaspiro[3.4]Octane is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.