Description

2-(5-Fluoropyridin-2-Yl)-2-Methylpropanoic Acid is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique structure, which incorporates both a fluoropyridine moiety and a sterically hindered carboxylic acid, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and central nervous system (CNS) active molecule libraries.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers and functional materials with tailored electronic or surface properties.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways due to its fluorinated aromatic system.

Basic Information

Product Name	2-(5-Fluoropyridin-2-Yl)-2-Methylpropanoic Acid
CAS No.	1057395-84-2
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	2-Methyl-2-(5-fluoropyridin-2-yl)propanoic acid; 2-(5-Fluoro-2-pyridinyl)-2-methylpropanoic acid; α,α-Dimethyl-5-fluoropicolinic acid; 5-Fluoro-2-(2-carboxypropan-2-yl)pyridine; 2-(5-Fluoropyridin-2-yl)-2-methylpropionic acid; 1057395-84-2; 2-(5-Fluoropyridin-2-yl)isobutyric acid
EINECS	Contact for details

Quality Control

Every batch of 2-(5-Fluoropyridin-2-Yl)-2-Methylpropanoic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.