Description

8-(3-Bromophenyl)-1,4-Dioxa-8-Azaspiro[4.5]Decane is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure containing a brominated phenyl group. This compound matters as a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) with complex molecular architectures. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of potential drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex molecules for central nervous system (CNS) and other therapeutic area research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, leveraging its halogenated aromatic moiety.
• Organic Chemistry Research: A valuable scaffold for medicinal chemists exploring structure-activity relationships (SAR) in drug discovery programs.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Potential monomer or additive for creating polymers with specific electronic or structural properties.

Basic Information

Product Name	8-(3-Bromophenyl)-1,4-Dioxa-8-Azaspiro[4.5]Decane
CAS No.	1057281-16-9
Molecular Formula	C15H18BrNO2
Molecular Weight	324.21 g/mol
Synonyms	8-(3-Bromophenyl)-1,4-dioxa-8-azaspiro[4.5]decane; 3-Bromo-N-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)benzenamine; 8-(3-Bromophenyl)-8-aza-1,4-dioxaspiro[4.5]decane; 1,4-Dioxa-8-azaspiro[4.5]decane, 8-(3-bromophenyl)-; 3-Bromophenyl-1,4-dioxa-8-azaspiro[4.5]decane; 8-(m-Bromophenyl)-1,4-dioxa-8-azaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Our 8-(3-Bromophenyl)-1,4-Dioxa-8-Azaspiro[4.5]Decane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliable supply for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.