Description

4-Amino-5-Bromo-6-Ethoxypicolinic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in modern organic synthesis. Its unique molecular structure, featuring amino, bromo, and ethoxy substituents on a picolinic acid core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a critical building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal catalysis and in the creation of novel organocatalysts for asymmetric synthesis.
• Material Science Research: Employed as a monomer or functionalizing agent in the synthesis of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and mechanisms.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in bespoke synthesis projects for clients.

Basic Information

Product Name	4-Amino-5-Bromo-6-Ethoxypicolinic Acid
CAS No.	1057260-48-6
Molecular Formula	C8H9BrN2O3
Molecular Weight	261.08 g/mol
Synonyms	5-Bromo-6-ethoxy-4-aminopicolinic acid; 4-Amino-5-bromo-6-ethoxy-2-pyridinecarboxylic acid; 6-Ethoxy-4-amino-5-bromopicolinic acid; 2-Pyridinecarboxylic acid, 4-amino-5-bromo-6-ethoxy-; ABEPA (abbreviation); 4-Amino-5-bromo-6-ethoxypyridine-2-carboxylic acid; 5-Bromo-4-amino-6-ethoxypicolinic acid
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Bromo-6-Ethoxypicolinic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed and under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.