Description

3-Hydroxy-1,5-naphthyridine-4-carbaldehyde is a high-purity, functionalized naphthyridine derivative serving as a critical advanced intermediate in organic synthesis. Its value lies in its unique fused heterocyclic structure, which provides a versatile scaffold for constructing complex molecules with potential biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry, drug discovery programs, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the naphthyridine core is pharmacologically relevant.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization studies to explore structure-activity relationships (SAR) and develop new therapeutic agents.
• Agrochemical Development: Serves as a precursor in the creation of new pesticides, herbicides, or fungicides that leverage its heterocyclic framework.
• Ligand Synthesis: The aldehyde and hydroxy functional groups make it a valuable starting material for constructing chelating ligands used in catalysis or metal coordination chemistry.
• Material Science Precursor: Potential use in the development of organic electronic materials or fluorescent dyes due to its conjugated system.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for fundamental chemical research and custom synthesis projects.

Basic Information

Product Name	3-Hydroxy-1,5-Naphthyridine-4-Carbaldehyde
CAS No.	1056877-14-5
Molecular Formula	C9H6N2O2
Molecular Weight	174.16 g/mol
Synonyms	1,5-Naphthyridine-4-carboxaldehyde, 3-hydroxy-; 3-Hydroxy-1,5-naphthyridine-4-carboxaldehyde; 4-Formyl-3-hydroxy-1,5-naphthyridine; 3-Hydroxy-1,5-naphthyridine-4-carbaldehyde; 1056877-14-5; 3-Hydroxy-1,5-naphthyridine-4-carboxylic aldehyde
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-1,5-naphthyridine-4-carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.