Description

(R)-tert-Butyl 2-(2-Hydroxyethyl)Azetidine-1-Carboxylate is a high-value, chiral azetidine derivative protected with a Boc (tert-butoxycarbonyl) group. This compound serves as a critical pharmaceutical intermediate and advanced building block for the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new drug candidates, particularly in areas requiring stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular architectures, especially those containing the azetidine ring system.
• Asymmetric Synthesis: Employed in stereoselective reactions to introduce chiral centers into target molecules.
• Protease Inhibitor Research: Potential precursor in the development of enzyme inhibitors due to the azetidine scaffold.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes for studying biological systems.
• Agrochemical Research: Intermediate in the development of new, high-performance crop protection agents.

Basic Information

Item	Detail
Product Name	(R)-tert-Butyl 2-(2-Hydroxyethyl)Azetidine-1-Carboxylate
CAS No.	1056166-09-6
Molecular Formula	C10H19NO3
Molecular Weight	201.26 g/mol
Synonyms	(R)-1-Boc-2-(2-hydroxyethyl)azetidine; (R)-tert-Butyl 2-(2-hydroxyethyl)azetidine-1-carboxylate; (R)-1-(tert-Butoxycarbonyl)-2-(2-hydroxyethyl)azetidine; (R)-2-(2-Hydroxyethyl)-1-azetidinecarboxylic acid 1,1-dimethylethyl ester; (R)-1-N-Boc-2-(2-hydroxyethyl)azetidine; (R)-Azetidine-1-carboxylic acid, 2-(2-hydroxyethyl)-, 1,1-dimethylethyl ester; (R)-Boc-2-(2-hydroxyethyl)azetidine
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 2-(2-Hydroxyethyl)Azetidine-1-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.